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Lithium-induced Cardiotoxicity: A Rare Clinical Entity
Lithium has been used effectively used in the management of mood disorders, such as bipolar disease, acute mania, and hypomania. As the therapeutic index is very narrow for lithium, it is important to monitor lithium levels periodically to avoid toxic effects. Common toxic effects include diarrhea,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159167/ https://www.ncbi.nlm.nih.gov/pubmed/32300505 http://dx.doi.org/10.7759/cureus.7286 |
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author | Acharya, Sudeep Siddiqui, Abdul Hasan Anwar, Shamsuddin Habib, Saad Anwar, Shamsuddin |
author_facet | Acharya, Sudeep Siddiqui, Abdul Hasan Anwar, Shamsuddin Habib, Saad Anwar, Shamsuddin |
author_sort | Acharya, Sudeep |
collection | PubMed |
description | Lithium has been used effectively used in the management of mood disorders, such as bipolar disease, acute mania, and hypomania. As the therapeutic index is very narrow for lithium, it is important to monitor lithium levels periodically to avoid toxic effects. Common toxic effects include diarrhea, tremor, muscle weakness, ataxia, and myoclonus. Severe toxicity can present with seizures, coma, and death. Cardiotoxicity secondary to lithium is rarely reported in the medical literature and can range from dysrhythmias and cardiomyopathies to myocardial infarction. We describe an interesting case report of cardiac toxicity secondary to lithium in a bipolar patient managed conservatively in an intensive care setting. |
format | Online Article Text |
id | pubmed-7159167 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-71591672020-04-16 Lithium-induced Cardiotoxicity: A Rare Clinical Entity Acharya, Sudeep Siddiqui, Abdul Hasan Anwar, Shamsuddin Habib, Saad Anwar, Shamsuddin Cureus Cardiology Lithium has been used effectively used in the management of mood disorders, such as bipolar disease, acute mania, and hypomania. As the therapeutic index is very narrow for lithium, it is important to monitor lithium levels periodically to avoid toxic effects. Common toxic effects include diarrhea, tremor, muscle weakness, ataxia, and myoclonus. Severe toxicity can present with seizures, coma, and death. Cardiotoxicity secondary to lithium is rarely reported in the medical literature and can range from dysrhythmias and cardiomyopathies to myocardial infarction. We describe an interesting case report of cardiac toxicity secondary to lithium in a bipolar patient managed conservatively in an intensive care setting. Cureus 2020-03-16 /pmc/articles/PMC7159167/ /pubmed/32300505 http://dx.doi.org/10.7759/cureus.7286 Text en Copyright © 2020, Acharya et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiology Acharya, Sudeep Siddiqui, Abdul Hasan Anwar, Shamsuddin Habib, Saad Anwar, Shamsuddin Lithium-induced Cardiotoxicity: A Rare Clinical Entity |
title | Lithium-induced Cardiotoxicity: A Rare Clinical Entity |
title_full | Lithium-induced Cardiotoxicity: A Rare Clinical Entity |
title_fullStr | Lithium-induced Cardiotoxicity: A Rare Clinical Entity |
title_full_unstemmed | Lithium-induced Cardiotoxicity: A Rare Clinical Entity |
title_short | Lithium-induced Cardiotoxicity: A Rare Clinical Entity |
title_sort | lithium-induced cardiotoxicity: a rare clinical entity |
topic | Cardiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159167/ https://www.ncbi.nlm.nih.gov/pubmed/32300505 http://dx.doi.org/10.7759/cureus.7286 |
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