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Lithium-induced Cardiotoxicity: A Rare Clinical Entity

Lithium has been used effectively used in the management of mood disorders, such as bipolar disease, acute mania, and hypomania. As the therapeutic index is very narrow for lithium, it is important to monitor lithium levels periodically to avoid toxic effects. Common toxic effects include diarrhea,...

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Detalles Bibliográficos
Autores principales: Acharya, Sudeep, Siddiqui, Abdul Hasan, Anwar, Shamsuddin, Habib, Saad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159167/
https://www.ncbi.nlm.nih.gov/pubmed/32300505
http://dx.doi.org/10.7759/cureus.7286
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author Acharya, Sudeep
Siddiqui, Abdul Hasan
Anwar, Shamsuddin
Habib, Saad
Anwar, Shamsuddin
author_facet Acharya, Sudeep
Siddiqui, Abdul Hasan
Anwar, Shamsuddin
Habib, Saad
Anwar, Shamsuddin
author_sort Acharya, Sudeep
collection PubMed
description Lithium has been used effectively used in the management of mood disorders, such as bipolar disease, acute mania, and hypomania. As the therapeutic index is very narrow for lithium, it is important to monitor lithium levels periodically to avoid toxic effects. Common toxic effects include diarrhea, tremor, muscle weakness, ataxia, and myoclonus. Severe toxicity can present with seizures, coma, and death. Cardiotoxicity secondary to lithium is rarely reported in the medical literature and can range from dysrhythmias and cardiomyopathies to myocardial infarction. We describe an interesting case report of cardiac toxicity secondary to lithium in a bipolar patient managed conservatively in an intensive care setting.
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spelling pubmed-71591672020-04-16 Lithium-induced Cardiotoxicity: A Rare Clinical Entity Acharya, Sudeep Siddiqui, Abdul Hasan Anwar, Shamsuddin Habib, Saad Anwar, Shamsuddin Cureus Cardiology Lithium has been used effectively used in the management of mood disorders, such as bipolar disease, acute mania, and hypomania. As the therapeutic index is very narrow for lithium, it is important to monitor lithium levels periodically to avoid toxic effects. Common toxic effects include diarrhea, tremor, muscle weakness, ataxia, and myoclonus. Severe toxicity can present with seizures, coma, and death. Cardiotoxicity secondary to lithium is rarely reported in the medical literature and can range from dysrhythmias and cardiomyopathies to myocardial infarction. We describe an interesting case report of cardiac toxicity secondary to lithium in a bipolar patient managed conservatively in an intensive care setting. Cureus 2020-03-16 /pmc/articles/PMC7159167/ /pubmed/32300505 http://dx.doi.org/10.7759/cureus.7286 Text en Copyright © 2020, Acharya et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Acharya, Sudeep
Siddiqui, Abdul Hasan
Anwar, Shamsuddin
Habib, Saad
Anwar, Shamsuddin
Lithium-induced Cardiotoxicity: A Rare Clinical Entity
title Lithium-induced Cardiotoxicity: A Rare Clinical Entity
title_full Lithium-induced Cardiotoxicity: A Rare Clinical Entity
title_fullStr Lithium-induced Cardiotoxicity: A Rare Clinical Entity
title_full_unstemmed Lithium-induced Cardiotoxicity: A Rare Clinical Entity
title_short Lithium-induced Cardiotoxicity: A Rare Clinical Entity
title_sort lithium-induced cardiotoxicity: a rare clinical entity
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159167/
https://www.ncbi.nlm.nih.gov/pubmed/32300505
http://dx.doi.org/10.7759/cureus.7286
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