The complicated clinical course in a case of atypical lipodystrophy after development of neutralizing antibody to metreleptin: treatment with setmelanotide

SUMMARY: A patient with atypical partial lipodystrophy who had a transient initial response to metreleptin experienced acute worsening of her metabolic state when neutralizing antibodies against metreleptin appeared. Because her metabolic status continued to deteriorate, a therapeutic trial with mel...

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Detalles Bibliográficos
Autores principales: Akinci, Baris, Meral, Rasimcan, Rus, Diana, Hench, Rita, Neidert, Adam H, DiPaola, Frank, Westerhoff, Maria, Taylor, Simeon I, Oral, Elif A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2020
Materias:
Novel Treatment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159256/
https://www.ncbi.nlm.nih.gov/pubmed/32213649
http://dx.doi.org/10.1530/EDM-19-0139

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