Cargando…
TMEM16A Potentiation: A Novel Therapeutic Approach for the Treatment of Cystic Fibrosis
Rationale: Enhancing non–CFTR (cystic fibrosis transmembrane conductance regulator)-mediated anion secretion is an attractive therapeutic approach for the treatment of cystic fibrosis (CF) and other mucoobstructive diseases. Objectives: To determine the effects of TMEM16A potentiation on epithelial...
Autores principales: | Danahay, Henry L., Lilley, Sarah, Fox, Roy, Charlton, Holly, Sabater, Juan, Button, Brian, McCarthy, Clive, Collingwood, Stephen P., Gosling, Martin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Thoracic Society
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159426/ https://www.ncbi.nlm.nih.gov/pubmed/31898911 http://dx.doi.org/10.1164/rccm.201908-1641OC |
Ejemplares similares
-
TMEM16A: An Alternative Approach to Restoring Airway Anion Secretion in Cystic Fibrosis?
por: Danahay, Henry, et al.
Publicado: (2020) -
Niclosamide does not modulate airway epithelial function through blocking of the calcium activated chloride channel, TMEM16A
por: Danahay, Henry, et al.
Publicado: (2023) -
Potentiating TMEM16A does not stimulate airway mucus secretion or bronchial and pulmonary arterial smooth muscle contraction
por: Danahay, Henry, et al.
Publicado: (2020) -
Reply to Olschewski et al.: TMEM16A Potentiation:
Possible Drawbacks
por: Danahay, Henry L., et al.
Publicado: (2020) -
TMEM16A in Cystic Fibrosis: Activating or Inhibiting?
por: Kunzelmann, Karl, et al.
Publicado: (2019)