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Isoelectric point region pI≈7.4 as a treasure island of abnormal proteoforms in blood
Theoretical distribution of isoelectric points (pI values) of human blood proteins exhibits multi-modality with a deep minimum in the range between pI 7.30 and 7.50. Considering that the pH of human blood is 7.4±0.1, normal forms of human proteins tend to eschew this specific pI region, thus avoidin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Applied Systems srl
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159840/ https://www.ncbi.nlm.nih.gov/pubmed/32309586 http://dx.doi.org/10.15190/d.2016.14 |