PHF20L1 as a H3K27me2 reader coordinates with transcriptional repressors to promote breast tumorigenesis

TUDOR domain–containing proteins (TDRDs) are chiefly responsible for recognizing methyl-lysine/arginine residue. However, how TDRD dysregulation contributes to breast tumorigenesis is poorly understood. Here, we report that TUDOR domain–containing PHF20L1 as a H3K27me2 reader exerts transcriptional...

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Detalles Bibliográficos
Autores principales: Hou, Yongqiang, Liu, Wei, Yi, Xianfu, Yang, Yang, Su, Dongxue, Huang, Wei, Yu, Hefen, Teng, Xu, Yang, Ying, Feng, Wei, Zhang, Tao, Gao, Jie, Zhang, Kai, Qiu, Rongfang, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159910/
https://www.ncbi.nlm.nih.gov/pubmed/32494608
http://dx.doi.org/10.1126/sciadv.aaz0356

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