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Revealing in real-time a multistep assembly mechanism for SV40 virus-like particles
Many viruses use their genome as template for self-assembly into an infectious particle. However, this reaction remains elusive because of the transient nature of intermediate structures. To elucidate this process, optical tweezers and acoustic force spectroscopy are used to follow viral assembly in...
Autores principales: | van Rosmalen, Mariska G. M., Kamsma, Douwe, Biebricher, Andreas S., Li, Chenglei, Zlotnick, Adam, Roos, Wouter H., Wuite, Gijs J.L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159915/ https://www.ncbi.nlm.nih.gov/pubmed/32494611 http://dx.doi.org/10.1126/sciadv.aaz1639 |
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