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Revealing in real-time a multistep assembly mechanism for SV40 virus-like particles

Many viruses use their genome as template for self-assembly into an infectious particle. However, this reaction remains elusive because of the transient nature of intermediate structures. To elucidate this process, optical tweezers and acoustic force spectroscopy are used to follow viral assembly in...

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Detalles Bibliográficos
Autores principales: van Rosmalen, Mariska G. M., Kamsma, Douwe, Biebricher, Andreas S., Li, Chenglei, Zlotnick, Adam, Roos, Wouter H., Wuite, Gijs J.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159915/
https://www.ncbi.nlm.nih.gov/pubmed/32494611
http://dx.doi.org/10.1126/sciadv.aaz1639

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