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The potassium channel Kcne3 is a VEGFA-inducible gene selectively expressed by vascular endothelial tip cells
Angiogenesis is largely driven by motile endothelial tip-cells capable of invading avascular tissue domains and enabling new vessel formation. Highly responsive to Vascular Endothelial Growth-Factor-A (VEGFA), endothelial tip-cells also suppress angiogenic sprouting in adjacent stalk cells, and thus...
Autores principales: | Deckelbaum, Ron A., Lobov, Ivan B., Cheung, Eunice, Halasz, Gabor, Rajamani, Saathyaki, Lerner, Julia, Tong, Chunxiang, Li, Zhe, Boland, Patricia, Dominguez, Melissa, Hughes, Virginia, Yancopoulos, George D., Murphy, Andrew J., Thurston, Gavin, Cao, Jingtai, Romano, Carmelo, Gale, Nicholas W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160073/ https://www.ncbi.nlm.nih.gov/pubmed/31754927 http://dx.doi.org/10.1007/s10456-019-09696-8 |
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