A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division

Genome stability relies on proper coordination of mitosis and cytokinesis, where dynamic microtubules capture and faithfully segregate chromosomes into daughter cells. With a high-content RNAi imaging screen targeting more than 2,000 human lncRNAs, we identify numerous lncRNAs involved in key steps...

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Detalles Bibliográficos
Autores principales: Stojic, Lovorka, Lun, Aaron T. L., Mascalchi, Patrice, Ernst, Christina, Redmond, Aisling M., Mangei, Jasmin, Barr, Alexis R., Bousgouni, Vicky, Bakal, Chris, Marioni, John C., Odom, Duncan T., Gergely, Fanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160116/
https://www.ncbi.nlm.nih.gov/pubmed/32296040
http://dx.doi.org/10.1038/s41467-020-14978-7

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