Cargando…
Preserving Airway Smooth Muscle Contraction in Precision-Cut Lung Slices
Precision-cut lung slices (PCLS) are ideal for measuring small airway contraction. However, these measurements are currently limited to acute exposure scenarios that typically last a few minutes to a few hours. Using an insulin-supplemented culture medium, we prolong the small airway contractility i...
Autores principales: | Li, Guang, Cohen, Jonathan A., Martines, Carolina, Ram-Mohan, Sumati, Brain, Joseph D., Krishnan, Ramaswamy, Ai, Xingbin, Bai, Yan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160136/ https://www.ncbi.nlm.nih.gov/pubmed/32296115 http://dx.doi.org/10.1038/s41598-020-63225-y |
Ejemplares similares
-
Inhibiting Airway Smooth Muscle Contraction Using Pitavastatin: A Role for the Mevalonate Pathway in Regulating Cytoskeletal Proteins
por: Lu, Robin A., et al.
Publicado: (2020) -
Airway and Parenchymal Strains during Bronchoconstriction in the Precision Cut Lung Slice
por: Hiorns, Jonathan E., et al.
Publicado: (2016) -
Corrigendum: Airway and Parenchymal Strains during Bronchoconstriction in the Precision Cut Lung Slice
por: Hiorns, Jonathan E., et al.
Publicado: (2017) -
A New Approach for the Study of Lung Smooth Muscle Phenotypes and Its Application in a Murine Model of Allergic Airway Inflammation
por: Paez-Cortez, Jesus, et al.
Publicado: (2013) -
A High-Throughput System for Cyclic Stretching of Precision-Cut Lung Slices During Acute Cigarette Smoke Extract Exposure
por: Mondoñedo, Jarred R., et al.
Publicado: (2020)