Cargando…

The TCR Repertoire Reconstitution in Multiple Sclerosis: Comparing One-Shot and Continuous Immunosuppressive Therapies

Natalizumab (NTZ) and autologous hematopoietic stem cell transplantation (AHSCT) are two successful treatments for relapsing-remitting multiple sclerosis (RRMS), an autoimmune T-cell-driven disorder affecting the central nervous system that is characterized by relapses interspersed with periods of c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Amoriello, Roberta, Greiff, Victor, Aldinucci, Alessandra, Bonechi, Elena, Carnasciali, Alberto, Peruzzi, Benedetta, Repice, Anna Maria, Mariottini, Alice, Saccardi, Riccardo, Mazzanti, Benedetta, Massacesi, Luca, Ballerini, Clara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160336/ https://www.ncbi.nlm.nih.gov/pubmed/32328061 http://dx.doi.org/10.3389/fimmu.2020.00559

Ejemplares similares

Investigating Serum sHLA-G Cooperation With MRI Activity and Disease-Modifying Treatment Outcome in Relapsing-Remitting Multiple Sclerosis
por: Amoriello, Roberta, et al.
Publicado: (2022)

TCR repertoire diversity in Multiple Sclerosis: High-dimensional bioinformatics analysis of sequences from brain, cerebrospinal fluid and peripheral blood
por: Amoriello, Roberta, et al.
Publicado: (2021)

Increased CXCL10 expression in MS MSCs and monocytes is unaffected by AHSCT
por: Bonechi, Elena, et al.
Publicado: (2014)

An innovative and affordable quantitative assessment of human TCR repertoire
por: Amoriello, Roberta, et al.
Publicado: (2020)

Immunosenescence and Autoimmunity: Exploiting the T-Cell Receptor Repertoire to Investigate the Impact of Aging on Multiple Sclerosis
por: Amoriello, Roberta, et al.
Publicado: (2021)

Autologous haematopoietic stem cell transplantation versus low‐dose immunosuppression in secondary–progressive multiple sclerosis
por: Mariottini, Alice, et al.
Publicado: (2022)

Intermediate-Intensity Autologous Hematopoietic Stem Cell Transplantation Reduces Serum Neurofilament Light Chains and Brain Atrophy in Aggressive Multiple Sclerosis
por: Mariottini, Alice, et al.
Publicado: (2022)

A non-traditional approach to cryopreservation by ultra-rapid cooling for human mesenchymal stem cells
por: Irdani, Tiziana, et al.
Publicado: (2019)

Anti-SARS-Cov2 vaccination at the time of the COVID-19 pandemic: suspected adverse events reporting is the milestone of post-marketing surveillance
por: Mariottini, Alice, et al.
Publicado: (2022)

Predominant Role of T Cell Receptor (TCR)-α Chain in Forming Preimmune TCR Repertoire Revealed by Clonal TCR Reconstitution System
por: Yokosuka, Tadashi, et al.
Publicado: (2002)

Hematopoietic Stem Cell Transplantation for the Treatment of Autoimmune Neurological Diseases: An Update
por: Mariottini, Alice, et al.
Publicado: (2023)

Local injection of bone marrow progenitor cells for the treatment of anal sphincter injury: in-vitro expanded versus minimally-manipulated cells
por: Mazzanti, Benedetta, et al.
Publicado: (2016)

CSF/serum matrix metallopeptidase‐9 ratio discriminates neuro Behçet from multiple sclerosis
por: Aldinucci, Alessandra, et al.
Publicado: (2018)

Graphene Oxide Nanosheets Reduce Astrocyte Reactivity to Inflammation and Ameliorate Experimental Autoimmune Encephalomyelitis
por: Di Mauro, Giuseppe, et al.
Publicado: (2023)

Cytokine inflammatory threat, but not LPS one, shortens GABAergic synaptic currents in the mouse spinal cord organotypic cultures
por: Giacco, Vincenzo, et al.
Publicado: (2019)

Maintenance of the EBV-specific CD8(+) TCRαβ repertoire in immunosuppressed lung transplant recipients
por: Nguyen, Thi HO, et al.
Publicado: (2017)

Safety and effectiveness of the booster dose of mRNA COVID-19 vaccines in people with multiple sclerosis: A monocentric experience()
por: Bertozzi, Andrea, et al.
Publicado: (2023)

Effect of disease-modifying treatments on antibody-mediated response to anti-COVID19 vaccination in people with multiple sclerosis
por: Mariottini, Alice, et al.
Publicado: (2022)

Huge Overlap of Individual TCR Beta Repertoires
por: Shugay, Mikhail, et al.
Publicado: (2013)

Human γδ TCR Repertoires in Health and Disease
por: Fichtner, Alina Suzann, et al.
Publicado: (2020)

Machine Learning Approaches to TCR Repertoire Analysis
por: Katayama, Yotaro, et al.
Publicado: (2022)

RRAS2 shapes the TCR repertoire by setting the threshold for negative selection
por: Martínez-Riaño, Ana, et al.
Publicado: (2019)

Diverse inflammatory threats modulate astrocytes Ca(2+) signaling via connexin43 hemichannels in organotypic spinal slices
por: Panattoni, Giulia, et al.
Publicado: (2021)

Characterization of the TCR V repertoire of piperacillin-specific T-cells
por: Al-Attar, Zaid, et al.
Publicado: (2014)

Analysis of the TCR Repertoire in HIV-Exposed but Uninfected Infants
por: Gabriel, Benjamin, et al.
Publicado: (2019)

Deciphering the TCR Repertoire to Solve the COVID-19 Mystery
por: Gutierrez, Lucas, et al.
Publicado: (2020)

Genetic and environmental determinants of human TCR repertoire diversity
por: Krishna, Chirag, et al.
Publicado: (2020)

Characterization of human αβTCR repertoire and discovery of D-D fusion in TCRβ chains
por: Liu, Peipei, et al.
Publicado: (2014)

Human thymic putative CD8αα precursors exhibit a biased TCR repertoire in single cell AIRR-seq
por: Heimli, Marte, et al.
Publicado: (2023)

Myelin-specific T cells carry and release magnetite PGLA–PEG COOH nanoparticles in the mouse central nervous system
por: D'Elios, M. M., et al.
Publicado: (2018)

A set point in the selection of the αβTCR T cell repertoire imposed by pre-TCR signaling strength
por: Bovolenta, Elena R., et al.
Publicado: (2022)

A TCR-switchable cell death pathway in T-ALL
por: Quang, Christine Tran, et al.
Publicado: (2017)

Skewing of the TCR V repertoire in SMX-NO specific T cell responses
por: Faulkner, Lee, et al.
Publicado: (2014)

Systematic Comparative Evaluation of Methods for Investigating the TCRβ Repertoire
por: Liu, Xiao, et al.
Publicado: (2016)

Accelerated Loss of TCR Repertoire Diversity in Common Variable Immunodeficiency
por: Wong, Gabriel K., et al.
Publicado: (2016)

TCR3d: The T cell receptor structural repertoire database
por: Gowthaman, Ragul, et al.
Publicado: (2019)

Inherent reactivity of unselected TCR repertoires to peptide-MHC molecules
por: Krovi, S. Harsha, et al.
Publicado: (2019)

Distorted TCR repertoires define multisystem inflammatory syndrome in children
por: Malik, Amna, et al.
Publicado: (2022)

Relevance of Pathogenetic Mechanisms to Clinical Effectiveness of B-Cell-Depleting Monoclonal Antibodies in Multiple Sclerosis
por: Massacesi, Luca, et al.
Publicado: (2022)

A discrete chromatin loop in the murine Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires
por: Chen, Liang, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_t6oso09garn8cph8dsg6pr4411