Epigenomic and Transcriptomic Changes During Human RPE EMT in a Stem Cell Model of Epiretinal Membrane Pathogenesis and Prevention by Nicotinamide

Epithelial to mesenchymal transition (EMT) is a biological process involved in tissue morphogenesis and disease that causes dramatic changes in cell morphology, migration, proliferation, and gene expression. The retinal pigment epithelium (RPE), which supports the neural retina, can undergo EMT, pro...

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Detalles Bibliográficos
Autores principales: Boles, Nathan C., Fernandes, Marie, Swigut, Tomasz, Srinivasan, Rajini, Schiff, Lauren, Rada-Iglesias, Alvaro, Wang, Qingjie, Saini, Janmeet S., Kiehl, Thomas, Stern, Jeffrey H., Wysocka, Joanna, Blenkinsop, Timothy A., Temple, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160390/
https://www.ncbi.nlm.nih.gov/pubmed/32243845
http://dx.doi.org/10.1016/j.stemcr.2020.03.009

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