C-KIT Expression Distinguishes Fetal from Postnatal Skeletal Progenitors

Hematopoietic stem cells (HSCs) and skeletal stem cells (SSCs) cohabit in the bone marrow. KITL (C-KIT ligand) from LEPR(+) adult bone marrow stromal cells is pivotal for HSC maintenance. In contrast, it remains unclear whether KITL/C-KIT signaling also regulates SSCs. Here, we lineage traced C-KIT(...

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Detalles Bibliográficos
Autores principales: He, Di Demi, Tang, Xinyu Thomas, Dong, Wenjie, Cui, Guizhong, Peng, Guangdun, Yin, Xiujuan, Chen, Yujie, Jing, Naihe, Zhou, Bo O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160391/
https://www.ncbi.nlm.nih.gov/pubmed/32220331
http://dx.doi.org/10.1016/j.stemcr.2020.03.001

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