Matrix Gla protein maintains normal and malignant hematopoietic progenitor cells by interacting with bone morphogenetic protein-4

Matrix Gla protein (MGP), a modulator of the BMP-SMAD signals, inhibits arterial calcification in a Glu γ-carboxylation dependent manner but the role of MGP highly expressed in a subset of bone marrow (BM) mesenchymal stem/stromal cells is unknown. Here we provide evidence that MGP might be a niche...

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Detalles Bibliográficos
Autores principales: Kuronuma, Kana, Yokoi, Aya, Fukuoka, Tomoya, Miyata, Muneaki, Maekawa, Akio, Tanaka, Satowa, Matsubara, Leo, Goto, Chie, Matsuo, Miki, Han, Hao-Wei, Tsuruta, Mai, Murata, Haruka, Okamoto, Hikari, Hasegawa, Natsumi, Asano, Shigetaka, Ito, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160454/
https://www.ncbi.nlm.nih.gov/pubmed/32322728
http://dx.doi.org/10.1016/j.heliyon.2020.e03743

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