Cargando…

miR-10a increases the cisplatin resistance of lung adenocarcinoma circulating tumor cells via targeting PIK3CA in the PI3K/Akt pathway

Circulating tumor cells (CTCs) that are shed from the primary tumor invade the blood stream or surrounding parenchyma to form new tumors. The present study aimed to explore the underlying mechanism of cisplatin resistance in lung adenocarcinoma CTCs and provide clinical treatment guidance for lung c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Tonghai, Ren, Kangqi, Ding, Guanggui, Yang, Lin, Wen, Yuxin, Peng, Bin, Wang, Guangsuo, Wang, Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160533/ https://www.ncbi.nlm.nih.gov/pubmed/32186774 http://dx.doi.org/10.3892/or.2020.7547

Ejemplares similares

Inhibition of Skp2 sensitizes lung cancer cells to paclitaxel
por: Huang, Tonghai, et al.
Publicado: (2017)

Mutations of PIK3CA in gastric adenocarcinoma
por: Li, Vivian Sze Wing, et al.
Publicado: (2005)

Dissection of PIK3CA Aberration for Cervical Adenocarcinoma Outcomes
por: Chung, Tony K. H., et al.
Publicado: (2021)

Lanthanum Chloride Causes Neurotoxicity in Rats by Upregulating miR-124 Expression and Targeting PIK3CA to Regulate the PI3K/Akt Signaling Pathway
por: Zheng, Linlin, et al.
Publicado: (2020)

circ_PTN contributes to -cisplatin resistance in glioblastoma via PI3K/AKT signaling through the miR-542-3p/PIK3R3 pathway
por: Luo, Hongcheng, et al.
Publicado: (2021)

Somatic frameshift mutation in PIK3CA causes CLOVES syndrome by provoking PI3K/AKT/mTOR pathway
por: Yan, Wei, et al.
Publicado: (2021)

Mutations in PI3K/AKT pathway genes and amplifications of PIK3CA are associated with patterns of recurrence in gastric cancers
por: Fang, Wen-Liang, et al.
Publicado: (2015)

Aspirin has a better effect on PIK3CA mutant colorectal cancer cells by PI3K/Akt/Raptor pathway
por: Chen, Zhihang, et al.
Publicado: (2020)

PIK3CA gene mutation associated with poor prognosis of lung adenocarcinoma
por: Zhang, Lina, et al.
Publicado: (2013)

Carcinogenesis of PIK3CA
por: German, Sidra, et al.
Publicado: (2013)

Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression
por: Huang, Xiaoxu, et al.
Publicado: (2019)

Activation of circ_0072088/miR‐1261/PIK3CA pathway accelerates lung adenocarcinoma progression
por: Cao, Feng, et al.
Publicado: (2022)

Alterations of INPP4B, PIK3CA and pAkt of the PI3K pathway are associated with squamous cell carcinoma of the lung
por: Stjernström, Annika, et al.
Publicado: (2014)

PIK3CA copy-number gain and inhibitors of the PI3K/AKT/mTOR pathway in triple-negative breast cancer
por: Amato, Ottavia, et al.
Publicado: (2023)

Long-Term Survival After Salvage Thoracic Surgery on a Patient with ALK-Rearranged Metastatic Lung Adenocarcinoma After Progression on Targeted Therapy
por: Ren, Kangqi, et al.
Publicado: (2021)

PIK3CA in Colorectal Cancer
por: Cathomas, Gieri
Publicado: (2014)

Correlation between circulating cell‐free PIK3CA tumor DNA levels and treatment response in patients with PIK3CA‐mutated metastatic breast cancer
por: Kodahl, Annette R., et al.
Publicado: (2018)

De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes
por: Rivière, Jean-Baptiste, et al.
Publicado: (2012)

Molecular and Functional Characterization of Three Different Postzygotic Mutations in PIK3CA-Related Overgrowth Spectrum (PROS) Patients: Effects on PI3K/AKT/mTOR Signaling and Sensitivity to PIK3 Inhibitors
por: Loconte, Daria C., et al.
Publicado: (2015)

PIK3CA copy number aberration and activation of the PI3K-AKT-mTOR pathway in varied disease states of penile cancer
por: Adimonye, Anthony, et al.
Publicado: (2018)

PIK3CA-mediated PI3-kinase signalling is essential for HPV-induced transformation in vitro
por: Henken, Florianne E, et al.
Publicado: (2011)

PIK3CA mutations can initiate pancreatic tumorigenesis and are targetable with PI3K inhibitors
por: Payne, S N, et al.
Publicado: (2015)

Mutational pattern of PIK3CA exon 20 in circulating DNA in breast cancer
por: Ibrahim, Iman Hassan, et al.
Publicado: (2022)

Mutation and prognostic analyses of PIK3CA in patients with completely resected lung adenocarcinoma
por: Song, Zhengbo, et al.
Publicado: (2016)

Prevalence and Prognostic Role of PIK3CA/AKT1 Mutations in Chinese Breast Cancer Patients
por: Deng, Ling, et al.
Publicado: (2019)

PIK3CA mutations are associated with increased tumor aggressiveness and Akt activation in gastric cancer
por: Kim, Ji-Won, et al.
Publicado: (2017)

miR-100-3p inhibits the adipogenic differentiation of hMSCs by targeting PIK3R1 via the PI3K/AKT signaling pathway
por: Wang, Tao, et al.
Publicado: (2020)

Mutations in PIK3CA are infrequent in neuroblastoma
por: Dam, Vincent, et al.
Publicado: (2006)

PIK3CA-mutations in breast cancer
por: Reinhardt, Kristin, et al.
Publicado: (2022)

PIK3CA and KRAS Amplification in Esophageal Adenocarcinoma and their Impact on the Inflammatory Tumor Microenvironment and Prognosis
por: Essakly, Ahlem, et al.
Publicado: (2019)

miR-10a overexpression aggravates renal ischemia–reperfusion injury associated with decreased PIK3CA expression
por: Xu, Dongsheng, et al.
Publicado: (2020)

Cezanne promoted autophagy through PIK3C3 stabilization and PIK3C2A transcription in lung adenocarcinoma
por: Wang, Yadong, et al.
Publicado: (2023)

Phenotypic and genetic spectrum of isolated macrodactyly: somatic mosaicism of PIK3CA and AKT1 oncogenic variants
por: Tian, Wen, et al.
Publicado: (2020)

RiPerC Attenuates Cerebral Ischemia Injury through Regulation of miR-98/PIK3IP1/PI3K/AKT Signaling Pathway
por: Zhang, Dengwen, et al.
Publicado: (2020)

PIK3IP1/TrIP restricts activation of T cells through inhibition of PI3K/Akt
por: Uche, Uzodinma U., et al.
Publicado: (2018)

A miR-567-PIK3AP1-PI3K/AKT-c-Myc feedback loop regulates tumour growth and chemoresistance in gastric cancer
por: Zhang, Feifei, et al.
Publicado: (2019)

PIK3CA Gene Amplification and PI3K p110α Protein Expression in Breast Carcinoma
por: Firoozinia, Mohammad, et al.
Publicado: (2014)

PIK3CA missense mutations promote glioblastoma pathogenesis, but do not enhance targeted PI3K inhibition
por: McNeill, Robert S., et al.
Publicado: (2018)

The role of the PIK3CA gene in the development and aging of the brain
por: Xie, Shaozhen, et al.
Publicado: (2021)

Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
por: Chen, Li, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7g2tnisblof1qn3dmontq9epio