Molecular Characterization of SehB, a Type II Antitoxin of Salmonella enterica Serotype Typhimurium: Amino Acid Residues Involved in DNA-Binding, Homodimerization, Toxin Interaction, and Virulence

Salmonella enterica serotype Typhimurium is a bacterium that causes gastroenteritis and diarrhea in humans. The genome of S. Typhimurium codes for diverse virulence factors, among which are the toxin-antitoxin (TA) systems. SehAB is a type II TA, where SehA is the toxin and SehB is the antitoxin. It...

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Detalles Bibliográficos
Autores principales: Chimal-Cázares, Fernando, Hernández-Martínez, Gabriela, Pacheco, Sabino, Ares, Miguel A., Soria-Bustos, Jorge, Sánchez-Gutiérrez, Manuel, Izquierdo-Vega, Jeannett A., Ibarra, Jose Antonio, González-y-Merchand, Jorge A., Gorvel, Jean-Pierre, Méresse, Stéphane, De la Cruz, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160566/
https://www.ncbi.nlm.nih.gov/pubmed/32328049
http://dx.doi.org/10.3389/fmicb.2020.00614

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