Inflammasome Is Activated in the Liver of Cholestatic Patients and Aggravates Hepatic Injury in Bile Duct–Ligated Mouse

BACKGROUND & AIMS: Inflammation plays an important role in the pathogenesis of cholestatic liver injury, but it is unclear whether the inflammasome is involved and is the objective of this study. METHODS: Gene expression was analyzed in the livers of patients with primary biliary cholangitis (n ...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Shi-Ying, Ge, Maoxu, Mennone, Albert, Hoque, Rafaz, Ouyang, Xinshou, Boyer, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160576/
https://www.ncbi.nlm.nih.gov/pubmed/31887435
http://dx.doi.org/10.1016/j.jcmgh.2019.12.008

Ejemplares similares

Ejemplares similares