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Characterization and Immunogenicity of HIV Envelope gp140 Zera(®) Tagged Antigens

HIV-1 envelope glycoprotein (Env) remains the most relevant target for the elicitation of functional antibodies to HIV by vaccination. However, soluble Env antigens often do not elicit the desired immune responses. Delivering subunit antigens on particulate nanoparticles is an established approach t...

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Detalles Bibliográficos
Autores principales: Ximba, Phindile, Chapman, Rosamund, Meyers, Ann E., Margolin, Emmanuel, van Diepen, Michiel T., Williamson, Anna-Lise, Rybicki, Edward P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160593/
https://www.ncbi.nlm.nih.gov/pubmed/32328488
http://dx.doi.org/10.3389/fbioe.2020.00321