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The Diversity Outbred Mouse Population Is an Improved Animal Model of Vaccination against Tuberculosis That Reflects Heterogeneity of Protection

Many studies of Mycobacterium tuberculosis infection and immunity have used mouse models. However, outcomes of vaccination and challenge with M. tuberculosis in inbred mouse strains do not reflect the full range of outcomes seen in people. Previous studies indicated that the novel Diversity Outbred...

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Detalles Bibliográficos
Autores principales:	Kurtz, Sherry L., Rossi, Amy P., Beamer, Gillian L., Gatti, Dan M., Kramnik, Igor, Elkins, Karen L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160682/ https://www.ncbi.nlm.nih.gov/pubmed/32295871 http://dx.doi.org/10.1128/mSphere.00097-20

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