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Comparing copy-number profiles under multi-copy amplifications and deletions
BACKGROUND: During cancer progression, malignant cells accumulate somatic mutations that can lead to genetic aberrations. In particular, evolutionary events akin to segmental duplications or deletions can alter the copy-number profile (CNP) of a set of genes in a genome. Our aim is to compute the ev...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160889/ https://www.ncbi.nlm.nih.gov/pubmed/32299350 http://dx.doi.org/10.1186/s12864-020-6611-3 |