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Establishment and characterization of patient-derived xenografts as paraclinical models for head and neck cancer

BACKGROUND: We investigated whether head and neck squamous cell carcinoma (HNSCC) patient-derived xenografts (PDXs) reaffirm patient responses to anti-cancer therapeutics. METHODS: Tumors from HNSCC patients were transplanted into immunodeficient mice and propagated via subsequent implantation. We e...

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Detalles Bibliográficos
Autores principales:	Kang, Han Na, Kim, Jae-Hwan, Park, A-Young, Choi, Jae Woo, Lim, Sun Min, Kim, Jinna, Shin, Eun Joo, Hong, Min Hee, Pyo, Kyoung-Ho, Yun, Mi Ran, Kim, Dong Hwi, Lee, Hanna, Yoon, Sun Och, Kim, Da Hee, Park, Young Min, Byeon, Hyung Kwon, Jung, Inkyung, Paik, Soonmyung, Koh, Yoon Woo, Cho, Byoung Chul, Kim, Hye Ryun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160896/ https://www.ncbi.nlm.nih.gov/pubmed/32293356 http://dx.doi.org/10.1186/s12885-020-06786-5

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