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An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania donovani amastigotes

BACKGROUND: Visceral leishmaniasis (VL) caused by dimorphic Leishmania species is a parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining control of VL in terms of proper and prevailing immunity development is a global necessity amid unavailability of a prophylactic...

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Detalles Bibliográficos
Autores principales: Khan, Md Anik Ashfaq, Ami, Jenifar Quaiyum, Faisal, Khaledul, Chowdhury, Rajashree, Ghosh, Prakash, Hossain, Faria, Abd El Wahed, Ahmed, Mondal, Dinesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160903/
https://www.ncbi.nlm.nih.gov/pubmed/32295617
http://dx.doi.org/10.1186/s13071-020-04064-8