Novel monoclonal antibodies against thymidine kinase 1 and their potential use for the immunotargeting of lung, breast and colon cancer cells

BACKGROUND: Thymidine kinase 1 (TK1) is a pyrimidine salvage pathway enzyme that is up-regulated in malignant tissues and elevated in the serum of cancer patients. While TK1 has been well established as a tumor biomarker, little has been done to explore its potential as a tumor target. Recently, we...

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Detalles Bibliográficos
Autores principales: Velazquez, Edwin J., Brindley, Taylor D., Shrestha, Gajendra, Bitter, Eliza E., Cress, Jordan D., Townsend, Michelle H., Berges, Bradford K., Robison, Richard A., Weber, K. Scott, O’Neill, Kim L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160906/
https://www.ncbi.nlm.nih.gov/pubmed/32317865
http://dx.doi.org/10.1186/s12935-020-01198-8

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