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Integrated analysis of transcriptomic and metabolomic profiling reveal the p53 associated pathways underlying the response to ionizing radiation in HBE cells

BACKGROUND: Radiation damage to normal tissues is a serious concern. P53 is a well-known transcription factor which is closely associated with radiation-induced cell damage. Increasing evidence has indicated that regulation of metabolism by p53 represents a reviving mechanism vital to protect cell s...

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Detalles Bibliográficos
Autores principales: Huang, Ruixue, Liu, Xiaodan, Li, He, Zhou, Yao, Zhou, Ping-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160934/
https://www.ncbi.nlm.nih.gov/pubmed/32318262
http://dx.doi.org/10.1186/s13578-020-00417-z