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LNK promotes the growth and metastasis of triple negative breast cancer via activating JAK/STAT3 and ERK1/2 pathway
BACKGROUND: LNK adaptor protein is a crucial regulator of normal hematopoiesis, which down-regulates activated tyrosine kinases at the cell surface resulting in an antitumor effect. To date, little studies have examined activities of LNK in solid tumors except ovarian cancer. METHODS: Clinical tissu...
Autores principales: | Lv, Jianxin, Yu, Wei, Zhang, Yanan, Cao, Xinhua, Han, Lifei, Hu, Haolin, Wang, Chenfei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160949/ https://www.ncbi.nlm.nih.gov/pubmed/32322171 http://dx.doi.org/10.1186/s12935-020-01197-9 |
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