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LNK promotes the growth and metastasis of triple negative breast cancer via activating JAK/STAT3 and ERK1/2 pathway

BACKGROUND: LNK adaptor protein is a crucial regulator of normal hematopoiesis, which down-regulates activated tyrosine kinases at the cell surface resulting in an antitumor effect. To date, little studies have examined activities of LNK in solid tumors except ovarian cancer. METHODS: Clinical tissu...

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Detalles Bibliográficos
Autores principales: Lv, Jianxin, Yu, Wei, Zhang, Yanan, Cao, Xinhua, Han, Lifei, Hu, Haolin, Wang, Chenfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160949/
https://www.ncbi.nlm.nih.gov/pubmed/32322171
http://dx.doi.org/10.1186/s12935-020-01197-9

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