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Direct Ultraviolet Laser-Induced Reduction of Disulfide Bonds in Insulin and Vasopressin

[Image: see text] Ultraviolet (UV) light has been shown to induce reduction of disulfide bonds in proteins in solution. The photoreduction is proposed to be a result of electron donation from excited Tyr or Trp residues. In this work, a powerful UV femtosecond laser was used to generate photoreduced...

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Detalles Bibliográficos
Autores principales: Gammelgaard, Simon K., Petersen, Steffen B., Haselmann, Kim F., Nielsen, Peter Kresten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161042/
https://www.ncbi.nlm.nih.gov/pubmed/32309706
http://dx.doi.org/10.1021/acsomega.9b04375

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