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Direct Ultraviolet Laser-Induced Reduction of Disulfide Bonds in Insulin and Vasopressin
[Image: see text] Ultraviolet (UV) light has been shown to induce reduction of disulfide bonds in proteins in solution. The photoreduction is proposed to be a result of electron donation from excited Tyr or Trp residues. In this work, a powerful UV femtosecond laser was used to generate photoreduced...
Autores principales: | Gammelgaard, Simon K., Petersen, Steffen B., Haselmann, Kim F., Nielsen, Peter Kresten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161042/ https://www.ncbi.nlm.nih.gov/pubmed/32309706 http://dx.doi.org/10.1021/acsomega.9b04375 |
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