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Epigenetic TET-Catalyzed Oxidative Products of 5-Methylcytosine Impede Z-DNA Formation of CG Decamers

[Image: see text] Methylation of cytosine has been known to play a significant role in epigenetic regulation. 5-Methylcytosine was among the first base modification that was discovered for the capability to facilitate B/Z-DNA transition as observed in CG repeated tracks. A study on gene repression b...

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Detalles Bibliográficos
Autores principales: Vongsutilers, Vorasit, Shinohara, Yoko, Kawai, Gota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161056/
https://www.ncbi.nlm.nih.gov/pubmed/32309715
http://dx.doi.org/10.1021/acsomega.0c00120

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