Cargando…

Berberine Ameliorates Prenatal Dihydrotestosterone Exposure-Induced Autism-Like Behavior by Suppression of Androgen Receptor

Many epidemiology studies have shown that maternal polycystic ovary syndrome (PCOS) results in a greater risk of autism spectrum disorders (ASD) development, although the detailed mechanism remains unclear. In this study, we aimed to investigate the potential mechanism and provide a possible treatme...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiang, Dongfang, Lu, Jianping, Wei, Chongxia, Cai, Xiaofan, Wang, Yongxia, Liang, Yujie, Xu, Mingtao, Wang, Zichen, Liu, Min, Wang, Min, Liang, Xuefang, Li, Ling, Yao, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cellular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161090/ https://www.ncbi.nlm.nih.gov/pubmed/32327976 http://dx.doi.org/10.3389/fncel.2020.00087

Ejemplares similares

SAT-412 Effects of the Ovary and Dihydrotestosterone on Firing Rate of GnRH Neurons in Prenatally Androgenized Mice
por: Dulka, Eden, et al.
Publicado: (2019)

Androgen deprivation promotes intratumoral synthesis of dihydrotestosterone from androgen metabolites in prostate cancer
por: Ishizaki, Fumio, et al.
Publicado: (2013)

Betulinic Acid Inhibits Endometriosis Through Suppression of Estrogen Receptor β Signaling Pathway
por: Xiang, Dongfang, et al.
Publicado: (2020)

Diversity of the Gut Microbiota in Dihydrotestosterone-Induced PCOS Rats and the Pharmacologic Effects of Diane-35, Probiotics, and Berberine
por: Zhang, Feifei, et al.
Publicado: (2019)

Prenatal Progestin Exposure Is Associated With Autism Spectrum Disorders
por: Li, Ling, et al.
Publicado: (2018)

Editorial: Endocrinological factors for autism: prenatal biomarkers, early diagnosis and symptom treatment
por: Liang, Yujie, et al.
Publicado: (2023)

Effects of Berberine on the Gastrointestinal Microbiota
por: Zhang, Lichao, et al.
Publicado: (2021)

Prenatal low-dose methyltestosterone, but not dihydrotestosterone, treatment induces penile formation in female mice and guinea pigs(†)
por: Wang, Shanshan, et al.
Publicado: (2020)

The progestational and androgenic properties of medroxyprogesterone acetate: gene regulatory overlap with dihydrotestosterone in breast cancer cells
por: Ghatge, Radhika P, et al.
Publicado: (2005)

Androgen dihydrotestosterone promotes bladder cancer cell proliferation and invasion via EPPK1-mediated MAPK/JUP signalling
por: Yang, Long, et al.
Publicado: (2023)

Hematopoietic stem cell transplantation ameliorates maternal diabetes–mediated gastrointestinal symptoms and autism‐like behavior in mouse offspring
por: Zeng, Jiaying, et al.
Publicado: (2022)

Profiles of 5α-Reduced Androgens in Humans and Eels: 5α-Dihydrotestosterone and 11-Ketodihydrotestosterone Are Active Androgens Produced in Eel Gonads
por: Yazawa, Takashi, et al.
Publicado: (2021)

The mechanism of berberine alleviating metabolic disorder based on gut microbiome
por: Wang, Han, et al.
Publicado: (2022)

Ursolic Acid Ameliorates Spinal Cord Injury in Mice by Regulating Gut Microbiota and Metabolic Changes
por: Rong, Zi-Jie, et al.
Publicado: (2022)

Reward-Related Behavioral, Neurochemical and Electrophysiological Changes in a Rat Model of Autism Based on Prenatal Exposure to Valproic Acid
por: Schiavi, Sara, et al.
Publicado: (2019)

The Estradiol-Dihydrotestosterone model of prostate cancer
por: Friedman, A Edward
Publicado: (2005)

Serum testosterone and dihydrotestosterone in carcinoma of the prostate.
por: Ghanadian, R., et al.
Publicado: (1979)

Tomato lipidic extract plus selenium decrease prostatic hyperplasia, dihydrotestosterone and androgen receptor expression versus finasteride in rats
por: Arias-Chávez, David Julian, et al.
Publicado: (2023)

6-sialyllactose ameliorates dihydrotestosterone-induced benign prostatic hyperplasia through suppressing VEGF-mediated angiogenesis
por: Kim, Eun-Yeong, et al.
Publicado: (2019)

A Potential Combination Therapy of Berberine Hydrochloride With Antibiotics Against Multidrug-Resistant Acinetobacter baumannii
por: Li, Xiaobo, et al.
Publicado: (2021)

Resveratrol ameliorates prenatal progestin exposure-induced autism-like behavior through ERβ activation
por: Xie, Weiguo, et al.
Publicado: (2018)

Maternal diabetes induces autism-like behavior by hyperglycemia-mediated persistent oxidative stress and suppression of superoxide dismutase 2
por: Wang, Xiumin, et al.
Publicado: (2019)

Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice
por: Xue, Mei, et al.
Publicado: (2015)

Dihydrotestosterone: Biochemistry, Physiology, and Clinical Implications of Elevated Blood Levels
por: Swerdloff, Ronald S., et al.
Publicado: (2017)

Dihydrotestosterone increases the risk of bladder cancer in men
por: Gil, Dorota, et al.
Publicado: (2019)

Dihydrotestosterone in Amyotrophic lateral sclerosis—The missing link?
por: Sawal, Nishit, et al.
Publicado: (2020)

Estradiol and Dihydrotestosterone Levels in COVID-19 Patients
por: MacArthur, Taleen A., et al.
Publicado: (2023)

Dihydrotestosterone Induces Arterial Stiffening in Female Mice
por: Horton, Alec C., et al.
Publicado: (2023)

Dihydrotestosterone Ameliorates Degeneration in Muscle, Axons and Motoneurons and Improves Motor Function in Amyotrophic Lateral Sclerosis Model Mice
por: Yoo, Young-Eun, et al.
Publicado: (2012)

Testosterone Reduces Knee Passive Range of Motion and Expression of Relaxin Receptor Isoforms via 5α-Dihydrotestosterone and Androgen Receptor Binding
por: Dehghan, Firouzeh, et al.
Publicado: (2014)

Anti-Cancer Activity of Novel Dihydrotestosterone-Derived Ring A-Condensed Pyrazoles on Androgen Non-Responsive Prostate Cancer Cell Lines
por: Mótyán, Gergő, et al.
Publicado: (2019)

Association between prenatal androgens and cord blood androgens, a path analysis
por: Xu, Hui, et al.
Publicado: (2023)

Inhibition of Caspase-1 Ameliorates Ischemia-Associated Blood-Brain Barrier Dysfunction and Integrity by Suppressing Pyroptosis Activation
por: Liang, Yubin, et al.
Publicado: (2021)

Alterations in Sensitivity to Estrogen, Dihydrotestosterone, and Xenogens in B-Lymphocytes from Children with Autism Spectrum Disorder and Their Unaffected Twins/Siblings
por: Sharpe, Martyn A., et al.
Publicado: (2013)

Altered Gut Microbiota in Chinese Children With Autism Spectrum Disorders
por: Ma, Bingjie, et al.
Publicado: (2019)

Berberine ameliorates non-alcoholic steatohepatitis in ApoE(−/−) mice
por: Yang, Jin, et al.
Publicado: (2017)

Assessment of the usefulness of dihydrotestosterone in the diagnostics of patients with androgenetic alopecia
por: Urysiak-Czubatka, Izabela, et al.
Publicado: (2014)

The effect of androgens on ovarian follicle maturation: Dihydrotestosterone suppress FSH-stimulated granulosa cell proliferation by upregulating PPARγ-dependent PTEN expression.
por: Chen, Mei-Jou, et al.
Publicado: (2015)

Transcript levels of 4 genes in umbilical cord blood are predictive of later autism development: a longitudinal follow-up study
por: Jia, Qingzheng, et al.
Publicado: (2023)

Berberine-Loaded Nanostructured Lipid Carriers Enhance the Treatment of Ulcerative Colitis
por: Deng, Jianping, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_dn1u7n3m6tmn3bvmsf2p03evp0