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Deep Reinforcement Learning for Data Association in Cell Tracking
Accurate target detection and association are vital for the development of reliable target tracking, especially for cell tracking based on microscopy images due to the similarity of cells. We propose a deep reinforcement learning method to associate the detected targets between frames. According to...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161216/ https://www.ncbi.nlm.nih.gov/pubmed/32328484 http://dx.doi.org/10.3389/fbioe.2020.00298 |
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author | Wang, Junjie Su, Xiaohong Zhao, Lingling Zhang, Jun |
author_facet | Wang, Junjie Su, Xiaohong Zhao, Lingling Zhang, Jun |
author_sort | Wang, Junjie |
collection | PubMed |
description | Accurate target detection and association are vital for the development of reliable target tracking, especially for cell tracking based on microscopy images due to the similarity of cells. We propose a deep reinforcement learning method to associate the detected targets between frames. According to the dynamic model of each target, the cost matrix is produced by conjointly considering various features of targets and then used as the input of a neural network. The proposed neural network is trained using reinforcement learning to predict a distribution over the association solution. Furthermore, we design a residual convolutional neural network that results in more efficient learning. We validate our method on two applications: the multiple target tracking simulation and the ISBI cell tracking. The results demonstrate that our approach based on reinforcement learning techniques could effectively track targets following different motion patterns and show competitive results. |
format | Online Article Text |
id | pubmed-7161216 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71612162020-04-23 Deep Reinforcement Learning for Data Association in Cell Tracking Wang, Junjie Su, Xiaohong Zhao, Lingling Zhang, Jun Front Bioeng Biotechnol Bioengineering and Biotechnology Accurate target detection and association are vital for the development of reliable target tracking, especially for cell tracking based on microscopy images due to the similarity of cells. We propose a deep reinforcement learning method to associate the detected targets between frames. According to the dynamic model of each target, the cost matrix is produced by conjointly considering various features of targets and then used as the input of a neural network. The proposed neural network is trained using reinforcement learning to predict a distribution over the association solution. Furthermore, we design a residual convolutional neural network that results in more efficient learning. We validate our method on two applications: the multiple target tracking simulation and the ISBI cell tracking. The results demonstrate that our approach based on reinforcement learning techniques could effectively track targets following different motion patterns and show competitive results. Frontiers Media S.A. 2020-04-09 /pmc/articles/PMC7161216/ /pubmed/32328484 http://dx.doi.org/10.3389/fbioe.2020.00298 Text en Copyright © 2020 Wang, Su, Zhao and Zhang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Bioengineering and Biotechnology Wang, Junjie Su, Xiaohong Zhao, Lingling Zhang, Jun Deep Reinforcement Learning for Data Association in Cell Tracking |
title | Deep Reinforcement Learning for Data Association in Cell Tracking |
title_full | Deep Reinforcement Learning for Data Association in Cell Tracking |
title_fullStr | Deep Reinforcement Learning for Data Association in Cell Tracking |
title_full_unstemmed | Deep Reinforcement Learning for Data Association in Cell Tracking |
title_short | Deep Reinforcement Learning for Data Association in Cell Tracking |
title_sort | deep reinforcement learning for data association in cell tracking |
topic | Bioengineering and Biotechnology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161216/ https://www.ncbi.nlm.nih.gov/pubmed/32328484 http://dx.doi.org/10.3389/fbioe.2020.00298 |
work_keys_str_mv | AT wangjunjie deepreinforcementlearningfordataassociationincelltracking AT suxiaohong deepreinforcementlearningfordataassociationincelltracking AT zhaolingling deepreinforcementlearningfordataassociationincelltracking AT zhangjun deepreinforcementlearningfordataassociationincelltracking |