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Deep Reinforcement Learning for Data Association in Cell Tracking

Accurate target detection and association are vital for the development of reliable target tracking, especially for cell tracking based on microscopy images due to the similarity of cells. We propose a deep reinforcement learning method to associate the detected targets between frames. According to...

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Detalles Bibliográficos
Autores principales: Wang, Junjie, Su, Xiaohong, Zhao, Lingling, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161216/
https://www.ncbi.nlm.nih.gov/pubmed/32328484
http://dx.doi.org/10.3389/fbioe.2020.00298
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author Wang, Junjie
Su, Xiaohong
Zhao, Lingling
Zhang, Jun
author_facet Wang, Junjie
Su, Xiaohong
Zhao, Lingling
Zhang, Jun
author_sort Wang, Junjie
collection PubMed
description Accurate target detection and association are vital for the development of reliable target tracking, especially for cell tracking based on microscopy images due to the similarity of cells. We propose a deep reinforcement learning method to associate the detected targets between frames. According to the dynamic model of each target, the cost matrix is produced by conjointly considering various features of targets and then used as the input of a neural network. The proposed neural network is trained using reinforcement learning to predict a distribution over the association solution. Furthermore, we design a residual convolutional neural network that results in more efficient learning. We validate our method on two applications: the multiple target tracking simulation and the ISBI cell tracking. The results demonstrate that our approach based on reinforcement learning techniques could effectively track targets following different motion patterns and show competitive results.
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spelling pubmed-71612162020-04-23 Deep Reinforcement Learning for Data Association in Cell Tracking Wang, Junjie Su, Xiaohong Zhao, Lingling Zhang, Jun Front Bioeng Biotechnol Bioengineering and Biotechnology Accurate target detection and association are vital for the development of reliable target tracking, especially for cell tracking based on microscopy images due to the similarity of cells. We propose a deep reinforcement learning method to associate the detected targets between frames. According to the dynamic model of each target, the cost matrix is produced by conjointly considering various features of targets and then used as the input of a neural network. The proposed neural network is trained using reinforcement learning to predict a distribution over the association solution. Furthermore, we design a residual convolutional neural network that results in more efficient learning. We validate our method on two applications: the multiple target tracking simulation and the ISBI cell tracking. The results demonstrate that our approach based on reinforcement learning techniques could effectively track targets following different motion patterns and show competitive results. Frontiers Media S.A. 2020-04-09 /pmc/articles/PMC7161216/ /pubmed/32328484 http://dx.doi.org/10.3389/fbioe.2020.00298 Text en Copyright © 2020 Wang, Su, Zhao and Zhang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Wang, Junjie
Su, Xiaohong
Zhao, Lingling
Zhang, Jun
Deep Reinforcement Learning for Data Association in Cell Tracking
title Deep Reinforcement Learning for Data Association in Cell Tracking
title_full Deep Reinforcement Learning for Data Association in Cell Tracking
title_fullStr Deep Reinforcement Learning for Data Association in Cell Tracking
title_full_unstemmed Deep Reinforcement Learning for Data Association in Cell Tracking
title_short Deep Reinforcement Learning for Data Association in Cell Tracking
title_sort deep reinforcement learning for data association in cell tracking
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161216/
https://www.ncbi.nlm.nih.gov/pubmed/32328484
http://dx.doi.org/10.3389/fbioe.2020.00298
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AT zhaolingling deepreinforcementlearningfordataassociationincelltracking
AT zhangjun deepreinforcementlearningfordataassociationincelltracking