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Tenascin-C predicts poor outcomes for patients with colorectal cancer and drives cancer stemness via Hedgehog signaling pathway
BACKGROUND: Tenascin-C (TNC) is an extracellular matrix protein that is widely expressed in the stromal fibroblasts of various cancers. However, the roles of TNC in colorectal cancer (CRC) cells remain unclear. METHODS: The expression of TNC, cancer stem cell-like (CSC) and cell cycle markers, and H...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161260/ https://www.ncbi.nlm.nih.gov/pubmed/32322169 http://dx.doi.org/10.1186/s12935-020-01188-w |