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Tenascin-C predicts poor outcomes for patients with colorectal cancer and drives cancer stemness via Hedgehog signaling pathway

BACKGROUND: Tenascin-C (TNC) is an extracellular matrix protein that is widely expressed in the stromal fibroblasts of various cancers. However, the roles of TNC in colorectal cancer (CRC) cells remain unclear. METHODS: The expression of TNC, cancer stem cell-like (CSC) and cell cycle markers, and H...

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Detalles Bibliográficos
Autores principales:	Yang, Zhaoting, Zhang, Chengye, Feng, Ying, Quan, Mingji, Cui, Yan, Xuan, Yanhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161260/ https://www.ncbi.nlm.nih.gov/pubmed/32322169 http://dx.doi.org/10.1186/s12935-020-01188-w

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