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Taxane-induced sensory peripheral neuropathy is associated with an SCN9A single nucleotide polymorphism in Japanese patients

BACKGROUND: Sodium channels located in the dorsal root ganglion, particularly Nav1.7 and Nav1.8, encoded by SCN9A and SCN10A, respectively, act as molecular gatekeepers for pain detection. Our aim was to determine the association between TIPN and SCN9A and SCN10A polymorphisms. METHODS: Three single...

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Detalles Bibliográficos
Autores principales:	Tanabe, Yuko, Shiraishi, Seiji, Hashimoto, Kenji, Ikeda, Kazutaka, Nishizawa, Daisuke, Hasegawa, Junko, Shimomura, Akihiko, Ozaki, Yukinori, Tamura, Nobuko, Yunokawa, Mayu, Yonemori, Kan, Takano, Toshimi, Kawabata, Hidetaka, Tamura, Kenji, Fujiwara, Yasuhiro, Shimizu, Chikako
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161266/ https://www.ncbi.nlm.nih.gov/pubmed/32295642 http://dx.doi.org/10.1186/s12885-020-06834-0

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