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NLRP12 collaborates with NLRP3 and NLRC4 to promote pyroptosis inducing ganglion cell death of acute glaucoma
BACKGROUND: Acute glaucoma, characterized by a sudden elevation in intraocular pressure (IOP) and retinal ganglion cells (RGCs) death, is a major cause of irreversible blindness worldwide that lacks approved effective therapies, validated treatment targets and clear molecular mechanisms. We sought t...
Autores principales: | Chen, Hui, Deng, Yang, Gan, Xiaoliang, Li, Yonghao, Huang, Wenyong, Lu, Lin, Wei, Lai, Su, Lishi, Luo, Jiawen, Zou, Bin, Hong, Yanhua, Cao, Yihai, Liu, Yizhi, Chi, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161290/ https://www.ncbi.nlm.nih.gov/pubmed/32295623 http://dx.doi.org/10.1186/s13024-020-00372-w |
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