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Limited recognition of Mycobacterium tuberculosis-infected macrophages by polyclonal CD4 and CD8 T cells from the lungs of infected mice

Immune responses following Mycobacterium tuberculosis (Mtb) infection or vaccination are frequently assessed by measuring T-cell recognition of crude Mtb antigens, recombinant proteins, or peptide epitopes. We previously showed that not all Mtb-specific T cells recognize Mtb-infected macrophages. Th...

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Detalles Bibliográficos
Autores principales:	Patankar, Yash R., Sutiwisesak, Rujapak, Boyce, Shayla, Lai, Rocky, Lindestam Arlehamn, Cecilia S., Sette, Alessandro, Behar, Samuel M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161428/ https://www.ncbi.nlm.nih.gov/pubmed/31636345 http://dx.doi.org/10.1038/s41385-019-0217-6

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