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Clinical Implications of SARS-CoV-2 Interaction With Renin Angiotensin System: JACC Review Topic of the Week

Severe acute respiratory-syndrome coronavirus-2 (SARS-CoV-2) host cell infection is mediated by binding to angiotensin-converting enzyme 2 (ACE2). Systemic dysregulation observed in SARS-CoV was previously postulated to be due to ACE2/angiotensin 1-7 (Ang1-7)/Mas axis downregulation; increased ACE2...

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Detalles Bibliográficos
Autores principales: Brojakowska, Agnieszka, Narula, Jagat, Shimony, Rony, Bander, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier on behalf of the American College of Cardiology Foundation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161517/
https://www.ncbi.nlm.nih.gov/pubmed/32305401
http://dx.doi.org/10.1016/j.jacc.2020.04.028