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Targeting Metabolism as a Platform for Inducing Allograft Tolerance in the Absence of Long-Term Immunosuppression
Transplant tolerance in the absence of long-term immunosuppression has been an elusive goal for solid organ transplantation. Recently, it has become clear that metabolic reprogramming plays a critical role in promoting T cell activation, differentiation, and function. Targeting metabolism can prefer...
Autores principales: | Cheng, Chih-Hsien, Lee, Chen-Fang, Oh, Byoung Chol, Furtmüller, Georg J., Patel, Chirag H., Brandacher, Gerald, Powell, Jonathan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161684/ https://www.ncbi.nlm.nih.gov/pubmed/32328063 http://dx.doi.org/10.3389/fimmu.2020.00572 |
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