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Streptococcus pneumoniae PepO promotes host anti-infection defense via autophagy in a Toll-like receptor 2/4 dependent manner

Macrophage is essential for host anti-bacterial defense by directly eliminating invading microbes and inducing a series of immune reactions. Here we identified a Streptococcus pneumoniae protein, PepO, as a TLR2/TLR4 bi-ligand. We found that PepO enhances macrophage unspecific phagocytosis and bacte...

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Detalles Bibliográficos
Autores principales:	Shu, Zhaoche, Yuan, Jun, Wang, Hong, Zhang, Jinghui, Li, Sijie, Zhang, Hong, Liu, Yusi, Yin, Yibing, Zhang, Xuemei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161686/ https://www.ncbi.nlm.nih.gov/pubmed/32172666 http://dx.doi.org/10.1080/21505594.2020.1739411

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