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Characterization of Schu S4 aro mutants as live attenuated tularemia vaccine candidates
There is a need for development of an effective vaccine against Francisella tularensis, as this potential bioweapon has a high mortality rate and low infectious dose when delivered via the aerosol route. Moreover, this Tier 1 agent has a history of weaponization. We engineered targeted mutations in...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161688/ https://www.ncbi.nlm.nih.gov/pubmed/32241221 http://dx.doi.org/10.1080/21505594.2020.1746557 |