Determining Whether Agonist Density or Agonist Number Is More Important for Immune Activation via Micoparticle Based Assay

It is unknown if surface bound toll-like-receptor (TLR) agonists activate cells via density or total molecular number. To answer this question, we developed a TLR agonist surface conjugated polystyrene microparticle (MP) system. Using a library of MPs with varying TLR agonist density and number, we...

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Detalles Bibliográficos
Autores principales: Deak, Peter, Kimani, Flora, Cassaidy, Brittney, Esser-Kahn, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161694/
https://www.ncbi.nlm.nih.gov/pubmed/32328073
http://dx.doi.org/10.3389/fimmu.2020.00642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161694/
https://www.ncbi.nlm.nih.gov/pubmed/32328073
http://dx.doi.org/10.3389/fimmu.2020.00642

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