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Determining Whether Agonist Density or Agonist Number Is More Important for Immune Activation via Micoparticle Based Assay
It is unknown if surface bound toll-like-receptor (TLR) agonists activate cells via density or total molecular number. To answer this question, we developed a TLR agonist surface conjugated polystyrene microparticle (MP) system. Using a library of MPs with varying TLR agonist density and number, we...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161694/ https://www.ncbi.nlm.nih.gov/pubmed/32328073 http://dx.doi.org/10.3389/fimmu.2020.00642 |