Identification of a novel PAK1 inhibitor to treat pancreatic cancer

Pancreatic cancer is one of the most aggressive cancers with poor prognosis and a low 5-year survival rate. The family of P21-activated kinases (PAKs) appears to modulate many signaling pathways that contribute to pancreatic carcinogenesis. In this work, we demonstrated that PAK1 is a critical regul...

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Detalles Bibliográficos
Autores principales: Wang, Jiaqi, Zhu, Yonghua, Chen, Jiao, Yang, Yuhan, Zhu, Lingxia, Zhao, Jiayu, Yang, Yang, Cai, Xueting, Hu, Chunping, Rosell, Rafael, Sun, Xiaoyan, Cao, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161699/
https://www.ncbi.nlm.nih.gov/pubmed/32322465
http://dx.doi.org/10.1016/j.apsb.2019.11.015

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