Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer's disease

Drug repurposing is an efficient strategy for new drug discovery. Our latest study found that nitazoxanide (NTZ), an approved anti-parasite drug, was an autophagy activator and could alleviate the symptom of Alzheimer's disease (AD). In order to further improve the efficacy and discover new che...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xiaokang, Lu, Jian, Xu, Yixiang, Wang, Jiaying, Qiu, Xiaoxia, Fan, Lei, Li, Baoli, Liu, Wenwen, Mao, Fei, Zhu, Jin, Shen, Xu, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161708/
https://www.ncbi.nlm.nih.gov/pubmed/32322468
http://dx.doi.org/10.1016/j.apsb.2019.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161708/
https://www.ncbi.nlm.nih.gov/pubmed/32322468
http://dx.doi.org/10.1016/j.apsb.2019.07.006

Ejemplares similares