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Synthesis, in vitro and in vivo biological evaluation of novel lappaconitine derivatives as potential anti-inflammatory agents

Lappaconitine (LA), a natural compound with a novel C18-diterpenoid alkaloid skeleton, displayed extensive biological profile. Recent research on LA is focused mainly on its anti-tumor and analgesic effects, and therefore we aimed to investigate its anti-inflammatory potential. A series of novel LA...

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Detalles Bibliográficos
Autores principales:	Pang, Lei, Liu, Chun-Yan, Gong, Guo-Hua, Quan, Zhe-Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161710/ https://www.ncbi.nlm.nih.gov/pubmed/32322467 http://dx.doi.org/10.1016/j.apsb.2019.09.002

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