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Synthesis, in vitro and in vivo biological evaluation of novel lappaconitine derivatives as potential anti-inflammatory agents
Lappaconitine (LA), a natural compound with a novel C18-diterpenoid alkaloid skeleton, displayed extensive biological profile. Recent research on LA is focused mainly on its anti-tumor and analgesic effects, and therefore we aimed to investigate its anti-inflammatory potential. A series of novel LA...
| Autores principales: | , , , |
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| Format: | Online Artículo Texto |
| Sprog: | English |
| Udgivet: |
Elsevier
2020
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| Fag: | |
| Online adgang: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161710/ https://www.ncbi.nlm.nih.gov/pubmed/32322467 http://dx.doi.org/10.1016/j.apsb.2019.09.002 |