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Disseminated Disease by Mycobacterium abscessus and Mycobacterium celatum in an Immunocompromised Host
Patient: Male, 62-year-old Final Diagnosis: Disseminated disease by Mycobacterium abscessus and Mycobacterium celatum Symptoms: Dyspnea • fever • pleural effusion • spleen nodules • splenomegaly Medication:— Clinical Procedure: — Specialty: Infectious Diseases OBJECTIVE: Rare disease BACKGROUND: Non...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161942/ https://www.ncbi.nlm.nih.gov/pubmed/32255770 http://dx.doi.org/10.12659/AJCR.921517 |
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author | Locatelli, Maria Elena Tosto, Salvatore D’Agata, Vincenzo Bonaventura, Paolo Grasso, Rosaria S. Marino, Andrea Pampaloni, Alessio Scuderi, Daniele Cosentino, Federica Cacopardo, Bruno |
author_facet | Locatelli, Maria Elena Tosto, Salvatore D’Agata, Vincenzo Bonaventura, Paolo Grasso, Rosaria S. Marino, Andrea Pampaloni, Alessio Scuderi, Daniele Cosentino, Federica Cacopardo, Bruno |
author_sort | Locatelli, Maria Elena |
collection | PubMed |
description | Patient: Male, 62-year-old Final Diagnosis: Disseminated disease by Mycobacterium abscessus and Mycobacterium celatum Symptoms: Dyspnea • fever • pleural effusion • spleen nodules • splenomegaly Medication:— Clinical Procedure: — Specialty: Infectious Diseases OBJECTIVE: Rare disease BACKGROUND: Nontuberculous mycobacteria (NTM) are environmental pathogens that cause an increasing number of diseases, in particular in immunosuppressed patients. Diagnosing NTM infections may be difficult because clinical presentation is unspecific and resembles other conditions such as tuberculosis, lymphomas, or septicemia. CASE REPORT: We report the case of a 62-year-old male with a recent history of autologous bone marrow transplantation for a follicular lymphoma admitted to our department for long-lasting remittent fever and abscess-like splenic nodules. The patient was diagnosed with mixed systemic infection by Mycobacterium abscessus and Mycobacterium celatum localized in spleen, bone marrow and kidneys. CONCLUSIONS: In this case a rare disseminated atypical mycobacteriosis was diagnosed and treated. As far as we know this is the first case in the literature of M. abscessus localization either in the spleen or in the bone marrow. Our patient underwent a complex long-term therapy and had a complete resolution of the disease. |
format | Online Article Text |
id | pubmed-7161942 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | International Scientific Literature, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71619422020-04-17 Disseminated Disease by Mycobacterium abscessus and Mycobacterium celatum in an Immunocompromised Host Locatelli, Maria Elena Tosto, Salvatore D’Agata, Vincenzo Bonaventura, Paolo Grasso, Rosaria S. Marino, Andrea Pampaloni, Alessio Scuderi, Daniele Cosentino, Federica Cacopardo, Bruno Am J Case Rep Articles Patient: Male, 62-year-old Final Diagnosis: Disseminated disease by Mycobacterium abscessus and Mycobacterium celatum Symptoms: Dyspnea • fever • pleural effusion • spleen nodules • splenomegaly Medication:— Clinical Procedure: — Specialty: Infectious Diseases OBJECTIVE: Rare disease BACKGROUND: Nontuberculous mycobacteria (NTM) are environmental pathogens that cause an increasing number of diseases, in particular in immunosuppressed patients. Diagnosing NTM infections may be difficult because clinical presentation is unspecific and resembles other conditions such as tuberculosis, lymphomas, or septicemia. CASE REPORT: We report the case of a 62-year-old male with a recent history of autologous bone marrow transplantation for a follicular lymphoma admitted to our department for long-lasting remittent fever and abscess-like splenic nodules. The patient was diagnosed with mixed systemic infection by Mycobacterium abscessus and Mycobacterium celatum localized in spleen, bone marrow and kidneys. CONCLUSIONS: In this case a rare disseminated atypical mycobacteriosis was diagnosed and treated. As far as we know this is the first case in the literature of M. abscessus localization either in the spleen or in the bone marrow. Our patient underwent a complex long-term therapy and had a complete resolution of the disease. International Scientific Literature, Inc. 2020-04-07 /pmc/articles/PMC7161942/ /pubmed/32255770 http://dx.doi.org/10.12659/AJCR.921517 Text en © Am J Case Rep, 2020 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) ) |
spellingShingle | Articles Locatelli, Maria Elena Tosto, Salvatore D’Agata, Vincenzo Bonaventura, Paolo Grasso, Rosaria S. Marino, Andrea Pampaloni, Alessio Scuderi, Daniele Cosentino, Federica Cacopardo, Bruno Disseminated Disease by Mycobacterium abscessus and Mycobacterium celatum in an Immunocompromised Host |
title | Disseminated Disease by Mycobacterium abscessus and Mycobacterium celatum in an Immunocompromised Host |
title_full | Disseminated Disease by Mycobacterium abscessus and Mycobacterium celatum in an Immunocompromised Host |
title_fullStr | Disseminated Disease by Mycobacterium abscessus and Mycobacterium celatum in an Immunocompromised Host |
title_full_unstemmed | Disseminated Disease by Mycobacterium abscessus and Mycobacterium celatum in an Immunocompromised Host |
title_short | Disseminated Disease by Mycobacterium abscessus and Mycobacterium celatum in an Immunocompromised Host |
title_sort | disseminated disease by mycobacterium abscessus and mycobacterium celatum in an immunocompromised host |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161942/ https://www.ncbi.nlm.nih.gov/pubmed/32255770 http://dx.doi.org/10.12659/AJCR.921517 |
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