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Treatment of mice with a ligand binding blocking anti-CD28 monoclonal antibody improves healing after myocardial infarction
Both conventional and regulatory CD4(+) T-cells rely on costimulatory signals mediated by cell surface receptors including CD28 for full activation. We showed previously that stimulation of CD4(+) Foxp3(+) regulatory T-cells by superagonistic anti-CD28 monoclonal antibodies (mAb) improves myocardial...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161974/ https://www.ncbi.nlm.nih.gov/pubmed/32298302 http://dx.doi.org/10.1371/journal.pone.0227734 |