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Functional Differences Between EBV- and CMV-Specific CD8(+) T cells Demonstrate Heterogeneity of T cell Dysfunction in CLL
Acquired T cell dysfunction is a hallmark of chronic lymphocytic leukemia (CLL), and is linked to an increased risk of infections, but also reduced immune surveillance and disappointing responses to autologous T cell-based immunotherapy. The mechanisms of T cell dysfunction in CLL are not well under...
Autores principales: | Hofland, Tom, de Weerdt, Iris, Endstra, Sanne, Jongejan, Aldo, Platenkamp, Laura, Remmerswaal, Ester B.M., Moerland, Perry D., ten Berge, Ineke J.M., Levin, Mark-David, Kater, Arnon P., Tonino, Sanne H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162091/ https://www.ncbi.nlm.nih.gov/pubmed/32309780 http://dx.doi.org/10.1097/HS9.0000000000000337 |
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