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Urine dicarboxylic acids change in pre-symptomatic Alzheimer’s disease and reflect loss of energy capacity and hippocampal volume

Non-invasive biomarkers will enable widespread screening and early diagnosis of Alzheimer’s disease (AD). We hypothesized that the considerable loss of brain tissue in AD will result in detection of brain lipid components in urine, and that these will change in concert with CSF and brain biomarkers...

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Detalles Bibliográficos
Autores principales:	Castor, K. J., Shenoi, S., Edminster, S. P., Tran, T., King, K. S., Chui, H., Pogoda, J. M., Fonteh, A. N., Harrington, M. G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162508/ https://www.ncbi.nlm.nih.gov/pubmed/32298384 http://dx.doi.org/10.1371/journal.pone.0231765

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