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Comparative genomics and full-length Tprk profiling of Treponema pallidum subsp. pallidum reinfection

Developing a vaccine against Treponema pallidum subspecies pallidum, the causative agent of syphilis, remains a public health priority. Syphilis vaccine design efforts have been complicated by lack of an in vitro T. pallidum culture system, prolific antigenic variation in outer membrane protein TprK...

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Detalles Bibliográficos
Autores principales: Addetia, Amin, Tantalo, Lauren C., Lin, Michelle J., Xie, Hong, Huang, Meei-Li, Marra, Christina M., Greninger, Alexander L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162541/
https://www.ncbi.nlm.nih.gov/pubmed/32251462
http://dx.doi.org/10.1371/journal.pntd.0007921