Cargando…
Comparative genomics and full-length Tprk profiling of Treponema pallidum subsp. pallidum reinfection
Developing a vaccine against Treponema pallidum subspecies pallidum, the causative agent of syphilis, remains a public health priority. Syphilis vaccine design efforts have been complicated by lack of an in vitro T. pallidum culture system, prolific antigenic variation in outer membrane protein TprK...
Autores principales: | Addetia, Amin, Tantalo, Lauren C., Lin, Michelle J., Xie, Hong, Huang, Meei-Li, Marra, Christina M., Greninger, Alexander L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162541/ https://www.ncbi.nlm.nih.gov/pubmed/32251462 http://dx.doi.org/10.1371/journal.pntd.0007921 |
Ejemplares similares
-
Estimation of Full-Length TprK Diversity in Treponema pallidum subsp. pallidum
por: Addetia, Amin, et al.
Publicado: (2020) -
Treponema pallidum subsp. pallidum with an Artificially impaired TprK antigenic variation system is attenuated in the Rabbit model of syphilis
por: Romeis, Emily, et al.
Publicado: (2023) -
Longitudinal TprK profiling of in vivo and in vitro-propagated Treponema pallidum subsp. pallidum reveals accumulation of antigenic variants in absence of immune pressure
por: Lin, Michelle J., et al.
Publicado: (2021) -
Genetic engineering of Treponema pallidum subsp. pallidum, the Syphilis Spirochete
por: Romeis, Emily, et al.
Publicado: (2021) -
Antimicrobial susceptibility of Treponema pallidum subspecies pallidum: an in-vitro study
por: Tantalo, Lauren C, et al.
Publicado: (2023)