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ZFYVE1 negatively regulates MDA5- but not RIG-I-mediated innate antiviral response

The retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs), including RIG-I and melanoma differentiation-associated gene 5 (MDA5), sense cytoplasmic viral RNA and initiate innate antiviral responses. How RIG-I and MDA5 are differentially regulated remains enigmatic. In this study, we identifie...

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Detalles Bibliográficos
Autores principales:	Zhong, Xuan, Feng, Lu, Zang, Ru, Lei, Cao-Qi, Yang, Qing, Shu, Hong-Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162542/ https://www.ncbi.nlm.nih.gov/pubmed/32251420 http://dx.doi.org/10.1371/journal.ppat.1008457

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